Total Synthesis of Complex Molecules
Total synthesis remains a pinnacle of chemical creativity, combining strategic planning, step economy, and deep mechanistic insight to construct intricate natural and designed molecules. Advances in retrosynthetic logic, cascade transformations, and selective functional group interconversions enable streamlined synthetic routes to structures with high stereochemical and architectural complexity. Innovations in catalytic enantioselective methods, biomimetic strategies, and radical-based transformations provide chemists with powerful tools to overcome synthetic bottlenecks. The synthesis of bioactive natural products continues to inspire new reaction development and enhances understanding of molecular function. Modern total synthesis also emphasizes sustainability, employing greener reagents, flow systems, and minimal-protection strategies. These efforts contribute significantly to drug discovery, chemical biology, and structural elucidation.
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Total Synthesis of Complex Molecules Conference Speakers
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- Advanced Catalytic Transformations
- AI-Driven Molecular Synthesis
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